Alanine

What is Alanine

Chemical Name: (S)-2-aminopropanoic acid

Molecular Weight: 89.1

Structrual Formula:

Nitrogen Content: 15.72%

Alanine (14,63,66)

L-Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system. BCAAs are used as a source of energy for muscle cells. During prolonged exercise, BCAAs are released from skeletal muscles and their carbon backbones are used as fuel, while their nitrogen portion is used to form another amino acid, Alanine. Alanine is then converted to Glucose by the liver. This form of energy production is called the Alanine-Glucose cycle, and it plays a major role in maintaining the body’s blood sugar balance.

L-Alanine is a white and odorless crystal powder with special sweet taste, which degree is about 70% of sugar. It easily dissolves in water (17% under 25), slightly dissolves in alcohol (0.2% in cold alcohol) and undissolves in ether. Ph value in 5% water solution equals 5.5 to 7.0.


L-Alanine is a kind of important amino acid formed proteins. In medicine, it is a main material syntheslsed Vitamin B6, composition of nutriments, and important composition of 800-14 amino acid injection new medicine for disease of liver and brain. In food, it can be used as flavouring, synthetic sweet agent and improving the aidity of organic acid. Also it can be used as additive of salted food, drink cotained alcohlos, oil, yolk sauce, and improving the taste of food made with dregs of rice.

Alanine and blood sugar level (56,59)

  • Glucose can be made from alanine in the liver or muscles when energy is needed, and thus it may help maintain the blood sugar level.
  • Alanine deficiency has been seen in hypoglycemia, and alanine supplementation may be helpful in treating this condition.
  • Alanine produces energy by stimulating glucagon secretions from the pancreas and is linked to glycogen released from the liver.
  • In cases of hypoglycemia (low blood sugar), alanine has been used as a source for the production of glucose in order to stabilize blood sugar over lengthy periods.
  • In fact, research is showing that taking an oral dose of the L form of alanine at bedtime, proved more effective for the insulin-dependent diabetic than a regular snack.

Alanine and cholesterol (57, 160)

  • Alanine also seems to have an effect on reducing cholesterol if combined with arginine and glycine.
  • When only arginine and alanine was used, cholesterol was reduced by 20%, but, with the addition of glycine, the results went up by a full 50%.

Alanine and Enlarged Prostate Gland

Alanine and immune system (58)

  • Alanine stimulates lymphocyte production and may help people who have immune suppression.

Alanine and brain (59)

  • Alanine is also an inhibitory or calming neurotransmitter in brain.

Deficiencies of alanine (60)

  • Deficiencies of alanine have been found in patients with hypoglycemia, diabetes, and alcohol-induced hepatitis.

Alanine in Food (63)

  • Alanine can be found in meat, poultry, fish, eggs, dairy products and some protein-rich plant foods.

Side Effects (61)

  • People with kidney or liver disease should not consume high intakes of amino acids without consulting a healthcare professional.

Reference

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